Living with severe multiple sclerosis: Cost-effectiveness of a palliative care intervention and cost of illness study

نویسندگان

چکیده

AbstractBackground Little is known about the economic consequences of living with severe multiple sclerosis (SMS). Aims To assess cost-effectiveness a home-based palliative approach (HPA) for people SMS (pwSMS). direct healthcare costs in this population. Methods PwSMS from three Italian centers received (2:1 ratio) HPA or usual care over six months. Direct were collected on monthly basis. Incremental was gauged national system (NHS) and personal perspective, considering Palliative Outcome Scale-Symptoms-MS (POS-S-MS) EuroQol five-dimension descriptive quality-adjusted life years (EQ-5D-3L QALYs), both completed at baseline, after Results Of 78 randomized pwSMS, 76 (50 HPA, 26 care) analyzed. Mean QALYs close to zero, mean group difference -0.006 (95% CI -0.057 0.044). The baseline-adjusted cost € -394 confidence interval, -3,532 2,743). POS-S-MS showed slight reduction symptom burden (-1.9; 95% -1.1 5.0) unchanged costs. due MS 23,195/year, almost equally distributed between NHS (€ 13,108) pwSMS 10,087). Personal care, medications home rehabilitation accounted 80% total expenditures. Most covered by these 3/4 out-of-pocket. Conclusions produced not associated an increase sustained Trial registration Current Controlled Trials ISRCTN73082124.

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ژورنال

عنوان ژورنال: Multiple sclerosis and related disorders

سال: 2021

ISSN: ['2211-0356', '2211-0348']

DOI: https://doi.org/10.1016/j.msard.2021.102756